1. In the thorax, each phrenic nerve supplies the mediastinal pleura and pericardium. 2. The phrenic nerve must be identified during thoracic surgery and preserved. 3. In canines the phrenic nerve arises from C5-C7 with occasional small contributions from C4. 4. Severing the phrenic nerve , or a phrenectomy, will paralyse that half of the diaphragm. 5. Raventoxin-VI blocks neuromuscular transmission in a rat phrenic nerve preparation. 6. Dozens of things irritate the phrenic nerves and cause hiccups. 7. Phrenic nerve interruption was introduced to Glen Lake in 1924.8. In the cat, horse, ox, and small ruminant the phrenic nerve arises variably from C4-C7. 9. Hiccups are fast, involuntary spasms of the diaphragm caused by irritation of those phrenic nerves . 10. The mediastinal and central portions of the diaphragmatic pleurae are innervated by the phrenic nerves .